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Autophagy

 

Autophagy is an alternative process of proteasomal degradation for some long-lived proteins or organelles. The process is important in normal cellular growth control and may be defective in tumor cells. Alterations in the autophagic-lysosomal compartment have also been linked to neuronal death in many neurodegenerative disorders as well as in transmissible neuronal pathologies (prion diseases).

Monoclonal antibodies against:

Beclin
LC3 B, N-Terminus
LC3 ABC

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