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Serine- Threonine kinases

 

Phosphorylation and dephosphorylation of cellular proteins are central steps in transducing extracellular signals to the cell nucleus. Phosphorylated epitopes may serve as docking sites for the assembly of protein complexes or may alter the 3-dimensional protein structure thus modulating enzymatic activity or the ability to undergo protein-protein interactions.
Modification of proteins on serine residues is mediated by serine/threonine kinases.

Monoclonal antibodies against:

c-raf

CKII substrate phosphopeptide
PKA substrate phosphopeptide
PKG substrate phosphopeptide
PDK substrate phosphopeptide

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